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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25e5fc68694ec6ba36ed935fb6d6a97b1fa8d465db4b441851a6f03dc19d599b' 
  AND token = 'CXnna4PcjVN+7jNdsS8XssIXpVL5KlABIuQ3aNgvDNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}