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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64ca80c9984fb87b44dd063b3a3ae7c604146b81602e617696ef4ccf932e164d' 
  AND token = '7qjmtNnjBW/1V0CstTkPQIo5WGcHCUaB5ScMZ9iTipk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}