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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d41008956a34254151556e7f0f4d4539b266adad0cc5fcebc7cdb7d473f106b' 
  AND token = '3hnIORPwLE0ecPziE9+1bRcjXdhyMvzdYzLt9BvaWCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}