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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81af4e84c7ded856a6f30d5904d3415e1177004be5eb5e0b87c8db1b0e50cae1' 
  AND token = 'kHrFLSU6mjCO+rtJzQ6HCnBUxdkXhUVvCFKRGIsB+lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}