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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6aa4e66d9904182d3cb7dd4e07ed217949d766d4d318bdb8444ac09f57ef08a4' 
  AND token = 'S6SiVT/wi/E6JZa/bvz7paYg2bONBa4qcR+/VM7r2IY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}