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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de04ff9078a179a21014a24432baaa9de93229e23643a7cc71b8f1db613cd26b' 
  AND token = 'gcTs9SxvHARpb//LX+tND3KSisACIapAm4iqkMBEImc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}