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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '144d2ea9f5d1c78eaf6902e2f688e856bf1381c57b66a190f752e3dbc4b2ef6e' 
  AND token = 'QO/Qfr9NG7pCV9YDzcVu7iQFgByWIh4WtHJB7rdeL6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}