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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc597aa36b03f0b6e1f01e38c4220ab76232812cf8342683d7ed66b6e9682da7' 
  AND token = 'PS8+mG5uqtiaV/v1/a3Hf7YnP1cHgsF2DOsjeOymdyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}