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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73165a77d42a8af6dd0f1dd70fa23ada76a90b8c7ff0ce21f35efa8e15b2c442' 
  AND token = 'k/grcF9Di8+7XTWywDRjAqZ74QNlu7um19OrAc1i22g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}