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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '405eb5f3a71ac88542196246f686ac520327fb53b29782f8dc142f8d5be19ec7' 
  AND token = 'RB5N3Dsodp1RPJhEcOAr37BXM5OKauwQouG1mk6h1mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}