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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e118063a009aba645bb0b0018b56182f0597aedb902748eea3c6f47baa1e5ae' 
  AND token = 'NdiV1Sn0LrMlxLfB/rk1N3JKMudv9jW2D610mdkItbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}