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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '491bcd7c7c0c2edee6709fd5fba5d4edc5eeb0d87b5374c37bcca4da1c82b944' 
  AND token = 'qRJFgiLcIz9BHl1nCqns4N5wtXEeZ6vGaA+NfInKiU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}