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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a6db424d5ecdc137e2bf6b56d497daad117fa7e923141c8e971815acf434864' 
  AND token = 'cjSc3sBQBPsbl1BLCBboy5eYtAjzTZmXG/T9zGzjWHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}