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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19eba590663a6fb1038a4bcffa3b478bc489f94a2c00b0bcbb9384dec5acb75a' 
  AND token = 'v22T4gsu5ymk+vcnkgsBRIHO8YwzQpLZ0IevCTrh5mM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}