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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a426c8b3c3585e5801ac22663c49acc65b0cadb9ceff4dc6528e4e99c73335f0' 
  AND token = 'qAKHV1Pnw9Fk8BO/oFgF0dsHeq0pr6ahL8XS7IVVASQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}