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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa3cce27e91a9ad6d784feabaf2355b91d7e7b78c229ca44ca8f1b69fda726a4' 
  AND token = 'SNEF9q96KrTorPyCnAKDMsRSdD1bpFor2ewIz2t8m5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}