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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1694b3e2f2752e4ee7ba2c0fd7a03bfdd0b4978febb06a5e4a28c05595023364' 
  AND token = 'y4ZyG7ofQsugc1COgqrikHqJ5VEvVYLCRaTqmtSYCNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}