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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53c12f3ebf40a64e869b1dac3e90fd9b69919ef6a75621b1f3c71e5710bea6a2' 
  AND token = 'XvYGyDUR/Ev7kPZRMbXW8XEJm60zKvRX7vCISqU77ZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}