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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c00d89c18b316d17ce9e4678ff37d280c4b1f4cd70ce4d903f79dcee0506669d' 
  AND token = 'FQk2jfxtTeSiZWhUSYjwk/8zFYWxRTm7q9O8niWZb3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}