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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5722d3ef7f2b9de6d2f909c2f96306ab524632effcc3db0e690f01cc85794931' 
  AND token = 'oyEg2kA5SAOYt511d+03vbpAu6YSEOt+uCWY1rk4dPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}