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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99722d8657403b4bff08c3fe9fbeaee2d0a715a7c4e8c7728704013fae7f9c23' 
  AND token = 'tMPIVGheQNdVIu8OxTx0JWNGaz1uxkM9N65x84GKd1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}