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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ccf385567754426064724bd98dc3ae686390c6cc2682f4db836f4b194f13a7b' 
  AND token = '8g4TCfLDOBWsbuuTJwb0RCcAn8uVbJ1+1spuMqV5lRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}