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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de12b16e27b98f46482e365dac3ffe9996f75aa20520d97df59d4a893fee9b00' 
  AND token = 'WHU4/6Rf7XEIXMj0ku0qabwpfUTA6Su9KO3ULR4iCjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}