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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a6ec04470332b9a7ce7214ef5cd020d5e5ebd36defbeff1b0d3b57904d2f6ab' 
  AND token = 'pMh3+91oWr2ZCaYFOC86Bj+80CXMK4cTGuTBef0ALeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}