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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a82cc7b89979cafd167c6a0fe4cf5f4b9ae928f1e7718255c49cc3e44534832' 
  AND token = 'C7qxW21F5g2qx07REPmhWQFDyjc453+qWd79xacDw48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}