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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5be6a064fd50d932292dee45a350b8ee48523b3a73eddf9667d01aa11425d5e4' 
  AND token = 'PWrG/dVcooN2EG9pdatRZwp2hoa9upk4yuPp2PqlXfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}