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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f025507eebbdd37d011737a126fd96966e6b3bdef128c28b15199a31ee79f9e9' 
  AND token = 'uGVPgfSnPc5x1hlK2iAfxbV2lqx/eGWKT/EtQ28xyzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}