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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f55c340216210d8d4b15b83b1f0a4b910d3e0853e7e0c9a5b9d6756178cefbf' 
  AND token = 'iRSG1VN+Zn7D4KkqNioI/Fb5aCv2dz7UU2wOkODzryw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}