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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ffbccb4cebfed42784d5f3db21148b37b6b9f0b81579fcaeb7c5631e4f9f486' 
  AND token = 'LOEDnLn97Jgxfr+rw0GWI2azzuP/zO1RI8eS1hBOYCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}