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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da2ad5a0a4584d6afb2a652d040a06865d5b5bbfdbfa95a0803c467895573ca6' 
  AND token = 'NkrOKg3skyFA/nUJI2C1BOD6E7DbUMaxdj3gsU5E1Yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}