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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67c3aa5cd53d69b8740be772eff357b287f781630ae90094fd8d9a759ff8b60f' 
  AND token = '+s/AlSNKTimdfUZGgO5hbkFRuG31GJUbfJMh74ZRuCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}