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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc9e0e62eee89a4ca069cee63a073358deecde66fd0d34f6816f8bdb3e8911c2' 
  AND token = 'NR/+wHDkLhBl+R1XTsNS08Ja0ZnGtw+MNVS0bi77HUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}