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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc8e9226de8c0b0fc499c3baed9664f3d452e997407f7f26e5e24fd48416d19f' 
  AND token = '+w7QkSlnnXmy6XQreMmfACopoEKOi5g+f1OHWOFvrD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}