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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '720415f2af9297bfa3160258173a36f5564889735c857b6358bb89f490da3442' 
  AND token = 'H7Xf5Wve56pyv4BNAZ+Krw+eHPWIFBLbcmKbqteUaaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}