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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4705bd3d16d2e83e5cb36dc1c57ba274dc29d1bbd3290fe4255dbca55c6ae6aa' 
  AND token = 'xEL+0zanlM8VquHbio/N+wZwPPt6eAaXSYZdpsY3L20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}