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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fee2457987c0298aa46bc965f6bc04480e83c8c4f4138b5852e5462a82233181' 
  AND token = '88QC8esorCd2c+FcQFcSamFU4OPafgFv92drmhyDlD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}