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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '906630854175d18a27f7eee0254292d4a254e1ecff867247f3da2a8d41c56fd4' 
  AND token = 'PNTAq1YfZFhADGMd01eOAmQMakUmna97djWqP18j7zU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}