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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ad00c3715efccec5ff68f85c52a50efbc44c6dc5c71849fd47e943b4f6c9e0f' 
  AND token = 'KDZqHJhfeEGMle6Pt9rj59mWZ+PnNgyN1dUZT/PDNZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}