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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f54c88c3919d23483e581ec4c878103e236276639ab7721a8aaad20ad72bdcfb' 
  AND token = '6l44QbJVz1u479/30BUZowi3lsow11AmyQOOmEIOoW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}