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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21de601b7fa186d40b0b937311ad1481c5e5d0e3c21c26edc775a51c2955419f' 
  AND token = '5Vd7IaP1g9qtn+ZZ1zuqObRWLMj4H7TyMmjNLy/zEwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}