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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1678ef42f627b32e749f32cd0446d62bc7bb2294995bb4f7accf6eb01a125b75' 
  AND token = '4WCTrEOu+IPgmd8Uj/0hmDL2TtBntgRDRz+j47zFBXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}