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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d942f785ac370306de500538bf5db820b0f03be9cf55b237b197b05668c7b74' 
  AND token = 'O2Tfwpzv5L4ay+B3LwP2iJz4vz0LqZvhVN6092VAm6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}