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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1693d06e98678f3a647fe1aaeca7394f51b7d4d37425bea0c0deace7e1a72338' 
  AND token = 'laSTL7Kzpi0PiKNyLwRDYHPAiEArcTb31zIbBwrR9Bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}