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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7aff4c0aecec70117a912c696638b0f9de2075b2a20543c8f550c3b075fed49' 
  AND token = 'q0UDqUiNYZeJUIFGqRSG7N5VRLqRsHXWYbZAKqEcQL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}