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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf2273a8f71c2d878f58150bba79222343918dd32c6970b386698c884c85eafc' 
  AND token = 'POFbcERLkNv8PcKIZ0Ch0TxloR37Ni8rcbUjZyWEtxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}