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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '073455707587c6d35b8e499bb9e92b12d1404cd9504ab9de5133fc9083b65081' 
  AND token = 'MW4Dq9ni3/iTiUUpPJcX0HfWiAOLJVvRaOEx3E+Rwlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}