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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09d41690526d8d6280d24d02615a9bba4f3451482dd98393e0d06572092abc0b' 
  AND token = '4ENs7+i4la1Bi/cfKFzWEzhKPUfEqvMu9yeQPtr4KrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}