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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3e51b7d7cb6c351e02af880665fbb550a76a65fa9167d4c218a20d0a2533796' 
  AND token = 'IYncI9VHnll10bWTORwnubwrpjkQZuomh5FZmD97x7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}