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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27763463ca39212910986ff2cd3c540abb0226eeb6057c48d5bdc8fa0a981eb8' 
  AND token = 'Ys+z8Vc6dPD8Nq4Jgp7zuGMY4ppRkNeAaVWNQpIw8FQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}