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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '943e5f299c760b4538f699191a92109c3b3f51b21a024af449c7b67a93cb0248' 
  AND token = 'SpGtiVpD5AU5JR6RrkrxwN8CLcLmYY3HntVngxhR3O8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}